Precocious Puberty: A Clinical Practice Guideline Education Activity (2026004HG)
Availability
On-Demand
Release on Jun 13, 2026 6:00 PM Central Daylight Time
Expires on Dec 31, 2028
Cost
$0.00
Credit Offered
1 AMA PRA Category 1 Credit
1 ABP-MOC Point
1 Participation Credit
  • Course Description
  • Target Audience
  • Learning Objectives
  • Accreditation Statement
  • Faculty and Disclosures
  • Recommended
Central precocious puberty (CPP), which is traditionally defined as the development of secondary sexual characteristics before age 8 years in girls and age 9 years in boys, results from the premature activation of the hypothalamic–pituitary–gonadal (HPG) axis. CPP can be associated with short adult stature, adverse psychosocial outcomes, and increased cardiometabolic and cancer risks in adulthood. Gonadotropin-releasing hormone (GnRH) agonists can effectively suppress premature activation of the HPG axis and have the potential to increase adult height as well as improve psychosocial and long-term health outcomes among patients with CPP. However, as secular trends have continued to shift toward earlier age of pubertal onset, some subpopulations of children with CPP, as it is currently defined, may not require the same extent of diagnostic evaluation and treatment.

This activity is a complement to the 2026 clinical practice guideline.
All clinicians that treat adolescents.
Upon completion of this activity, learners should be able to:
  • Identify evidence-based approaches for evaluating for central precocious puberty (CPP)
  • Select the recommended tests to diagnose CPP
  • Identify the appropriate treatment of CPP

The Endocrine Society is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Endocrine Society has achieved Accreditation with Commendation.

AMA PRA Category 1 Credit
The Endocrine Society designates each activity in this course for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. While offering CME credits noted above, this program is not intended to provide extensive training or certification in the field.

Please note that while other accrediting bodies accept AMA PRA Category 1 credit, we can only award and report this credit for MDs/DOs. For those outside of this accreditation, please complete the participation evaluation and use that certificate as proof of attendance to submit to your accrediting body.


Maintenance of Certification (MOC)
Successful completion of each CME activity in this course, which includes participation in the evaluation component, enables the participant to earn up to 1 points in the American Board of Pediatrics (ABP) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABP MOC credit.

For questions about content or obtaining CME credit, please contact the Endocrine Society at info@endocrine.org

Ana Pinheiro Machado Canton, MD, PhD
University of São Paulo (USP) Medical School 
São Paulo, Brazil

Paul B. Kaplowitz, MD, PhD
Children's National Medical Center
Washington, DC



STATEMENT OF INDEPENDENCE

As a provider of CME accredited by the Accreditation Council for Continuing Medical Education, the Endocrine Society has a policy of ensuring that the content and quality of this educational activity are balanced, independent, objective, and scientifically rigorous. The scientific content of this activity was developed under the supervision of the Endocrine Society’s peer reviewers.

DISCLOSURE POLICY
The faculty, committee members, and staff who are in position to control the content of this activity are required to disclose to the Endocrine Society and to learners any relevant financial relationship(s) of the individual that have occurred within the last 12 months with any commercial interest(s) whose products or services are related to the content. Financial relationships are defined by remuneration in any amount from the commercial interest(s) in the form of grants; research support; consulting fees; salary; ownership interest (e.g., stocks, stock options, or ownership interest excluding diversified mutual funds); honoraria or other payments for participation in speakers' bureaus, advisory boards, or boards of directors; or other financial benefits. The intent of this disclosure is not to prevent planners with relevant financial relationships from planning or delivery of content, but rather to provide learners with information that allows them to make their own judgments of whether these financial relationships may have influenced the educational activity with regard to exposition or conclusion.

The Endocrine Society has reviewed all disclosures and resolved or managed all identified conflicts of interest, as applicable.

The following faculty who developed the content for this CME activity reported no relevant financial relationships: Paul B. Kaplowitz, MD, PhD; Ana Pinheiro Machado Canton, MD, PhD

The following subject matter experts who developed the clinical practice guideline used to create this activity reported the following relevant financial relationships: 

  • Fernando Cassorla, MD: Speaker, Novo Nordisk, Pfizer, LUMOS; Investigator, Debiopharm; Research, LUMOS
  • Erica Eugster, MD: Research, Forsee; Advisry board, Neurocrine biosciences
  • Anna Grandone, MD, PhD: Advisory board, Kyowa kirin; Speaker, Novo Nordisk, Pfizer; Research, Novo Nordisk
  • Maria E. Street, MD, PhD: Consultant, Novo Nordisk; Advisory Board, Pfizer, Amryt; Speaker, Pfizer, Sandoz

The following subject matter experts who developed the clinical practice guideline used to create this activity reported no relevant financial relationships: Ana Claudia Latronico, MD, PhD; Stephanie Roberts; MD; Morgan Alonzo, PharmD; Evangelia Charmandari, MD, MSc, PhD; Jesus Argente, MD, PhD; Jean-Claude Carel, MD; Louise Greenspan, MD; Elizabeth Hawse, MD; Anderson Juul, MD, PhD; M. Hassan Murad, MD; Vayana Walker; Christopher R. McCartney, MD


The Endocrine Society staff involved in the development of this CME activity reported no relevant financial relationships.

   
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