The Hormonal Impact on Endometriosis – the Unseen Disease of Reproduction-The Hormonal Impact on Endometriosis

Video Transcription

Video Summary

Summary 1: <br />The video features Dr. Jessica Chan and Dr. Rob Taylor discussing the challenges of diagnosing and treating endometriosis. They explain that current diagnostic methods are inadequate and often involve surgery. Dr. Chan introduces the BME study that aims to understand the disease through single cell profiling. They have collected samples from approximately 450 patients and have identified distinct cellular and molecular biology characteristics of different types of endometriosis. Potential gene markers and therapeutic targets have been identified. They also explore the role of stem cells and circulating microRNAs in the systemic effects of endometriosis.<br /><br />Summary 2: <br />Dr. Julie Kim discusses the importance of models in studying endometriosis, focusing on induced pluripotent stem cells (iPSCs). iPSCs can be differentiated into various cell types, including endometrial stromal cells, and are used to study the genetic factors involved in endometriosis and cell differentiation. Dr. Kim introduces the Lattice microfluidic platform that automates iPSC differentiation and culture. She proposes using iPSCs to recreate endometriosis in vitro and investigate cell interactions. Dr. Kim highlights the need for novel approaches and collaboration in advancing research on endometriosis.<br /><br />No specific credits are mentioned in the video summary descriptions.

Keywords

endometriosis

diagnosis

treatment

surgery

BME study

gene markers

therapeutic targets

stem cells

circulating microRNAs

models

cell differentiation

research


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