Menopause Science and Clinical Care-Menopause Science and Clinical Care

Video Transcription

Video Summary

The session covers the rapidly evolving science and clinical care of menopause, emphasizing menopause physiology, recent research advancements, and follow-up studies from the Women's Health Initiative. A key principle highlighted is personalized medicine, considering individual patient risks for issues like fractures, breast cancer, cardiovascular disease, and menopause symptoms. Tools like FRAX, IVAS, and ACC/ASCVD are recommended for patient evaluation. Controversies in menopause hormone therapy, especially surrounding estrogen and breast cancer risk, are addressed with varying study results. Experts stress the importance of shared decision-making in treatment choices, focusing on symptom relief and lifestyle factors. The emergence of neurokinin antagonists like Fasalinatant and Elansenatant as new therapeutic options for vasomotor symptoms is discussed, showing promising results with fewer safety concerns. Continuous hormone therapy's risks and benefits—especially regarding cardiovascular health and breast cancer—and non-hormonal treatments are examined, highlighting the necessity of individualizing patient care. The talk encourages healthcare providers to deliver evidence-based, personalized menopause management and underscores the importance of ongoing patient-physician dialogue.

Keywords

menopause

personalized medicine

Women's Health Initiative

hormone therapy

neurokinin antagonists

cardiovascular disease

breast cancer

patient evaluation

shared decision-making


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