Life Cycle Considerations in Hypoparathyroidism-Hypoparathyroidism and Aging

Video Transcription

Video Summary

This presentation delves into the long-term consequences of hypoparathyroidism, highlighting its multisystem nature and the associated risks of renal and cardiovascular complications. A systemic review revealed common complications linked to this condition. Notably, hypoparathyroidism patients, particularly with prolonged and non-surgical cases, face heightened risks of renal issues, such as hypercalciuria and increased progression towards chronic kidney disease (CKD). Cardiovascular risks, including arrhythmias and ischemic heart disease, are also significant. Evidence from various studies indicates worsening complications with disease duration. While conventional therapies necessitate continuous monitoring to mitigate risks, PTH replacement therapies offer promising outcomes, notably reducing neuropsychiatric and renal complications, with studies showing improved biochemical control and decreased urinary calcium excretion. Despite these advancements, comprehensive patient care and vigilant monitoring remain crucial in managing hypoparathyroidism.

Keywords

hypoparathyroidism

renal complications

cardiovascular risks

PTH replacement therapy

chronic kidney disease


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