ITE 2026 Live (2026003HG)-Recording: ITE 2026 Live - Adrenal, Bone, Pituitary, Reproduction

Video Transcription

Video Summary

The session opened with Hannah Gittner and Dr. Nicholas Tritos explaining that ITE Live is meant to benchmark fellows’ progress rather than serve as board preparation. Faculty then reviewed several exam questions with lower correctness rates across adrenal, bone, pituitary, and reproduction.<br /><br />In adrenal, Dr. Correa discussed a young man with adrenal insufficiency and large adrenal masses whose correct diagnosis was congenital adrenal hyperplasia with adrenal myelolipomas, not metastases. He also reviewed an adrenal incidentaloma case where a small, lipid-rich, nonfunctioning adenoma required no further follow-up.<br /><br />In bone, Dr. Malabanan explained that stopping denosumab requires follow-on bisphosphonate therapy, with alendronate preferred to prevent rebound bone loss and vertebral fractures. He also reviewed a hypercalcemia case due to CYP24A1 mutation causing elevated calcitriol and kidney stones, and a Roux-en-Y gastric bypass stone-former whose best treatment included potassium citrate, increased fluids, and diet modification.<br /><br />In pituitary, Drs. Donangelo and Galman reviewed polyuria-polydipsia evaluation, emphasizing copeptin as the best diagnostic test after water deprivation, especially in suspected lithium-related nephrogenic diabetes insipidus. They also discussed immune checkpoint inhibitor hypophysitis: PD-1 therapy commonly causes isolated ACTH deficiency with a normal pituitary MRI.<br /><br />In reproduction, Dr. Stamou reviewed nonclassic congenital adrenal hyperplasia treated first with combined oral contraceptives when fertility is not desired, and confirmed ovulation best with mid-luteal progesterone. In male reproduction, she discussed retrograde ejaculation from diabetic autonomic neuropathy and a case of hCG abuse causing low LH, normal testosterone, gynecomastia, and preserved testicular size.<br /><br />The session ended with answers to audience questions and a preview of the next ITE Live topic areas.

Keywords

ITE Live

adrenal insufficiency

congenital adrenal hyperplasia

denosumab

bisphosphonate therapy

copeptin

hypophysitis

nonclassic congenital adrenal hyperplasia

retrograde ejaculation

hCG abuse


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