Dilemmas in Diabetes Mellitus in Youth-Dilemmas in Diabetes Mellitus in Youth

Video Transcription

Video Summary

The video discusses two cases related to diabetes. The first case involves a 10-year-old girl with a family history of type 2 diabetes who is diagnosed with pre-diabetes. The speaker emphasizes that the criteria for diagnosing pre-diabetes in youth have not been validated, and there is no known way to prevent progression to diabetes in these cases. The use of metformin as a treatment option is questioned, as studies have shown limited improvement in insulin sensitivity and beta cell function. The speaker suggests focusing on treating the weight-related issues and comorbidities instead. <br /><br />In the second case, a 17-year-old boy is diagnosed with type 2 diabetes, but later found to have pancreatic autoantibodies. The speaker highlights the importance of antibody testing in distinguishing type 1 and type 2 diabetes in youth, as clinical features are not sufficient for an accurate diagnosis. The boy's treatment is changed to insulin therapy, and the speaker recommends starting with basal insulin while initiating metformin. <br /><br />Overall, the video highlights the challenges in diagnosing and managing diabetes in youth, particularly in distinguishing between type 1 and type 2 diabetes. The speaker emphasizes the need for antibody testing and individualized treatment plans based on the specific characteristics of each case.

Keywords

diabetes

pre-diabetes

type 2 diabetes

metformin

insulin sensitivity

beta cell function

pancreatic autoantibodies

type 1 diabetes


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