Clinical Pearls from JCEM Case Reports: Pituitary Edition-Case Discussion: Ovarian Hyperstimulation Syndrome Caused by Functional Gonadotroph Pituitary Adenoma

Case Discussion: Ovarian Hyperstimulation Syndrome Caused by Functional Gonadotroph Pituitary Adenoma

Video Transcription

Video Summary

This webinar discusses a case report titled "Ovarian Hyperstimulation Syndrome Caused by a Functional Gonadotroph Pituitary Adenoma". The presenter, Dr. Ryo Tazukaguchi, describes the case of a 28-year-old woman who developed symptoms of lower abdominal pain, abdominal swelling, and dyspnea. She had a pituitary tumor that was initially considered non-functioning, but it was later discovered that she had a functional gonadotroph adenoma. The patient had irregular menstrual cycles and high levels of estrodiol, suppressed luteinizing hormone (LH), and non-suppressed follicle-stimulating hormone (FSH). She also had enlarged ovaries and developed ovarian hyperstimulation syndrome (OHSS), which presented as multiple ovarian cysts and pleural effusion. The patient was treated with carbergoline to improve her condition, but surgery was eventually performed to remove the tumor. The case highlights the rarity of OHSS caused by functional gonadotroph adenomas and the importance of considering this diagnosis in premenopausal females with symptoms of menstrual irregularities or pituitary tumors. The webinar also discusses the differential diagnosis of PCOS and estrogen-producing tumors, as well as the management options for functional gonadotroph adenomas.

Keywords

Ovarian Hyperstimulation Syndrome

Functional Gonadotroph Pituitary Adenoma

Case Report

Dr. Ryo Tazukaguchi

Lower Abdominal Pain

Abdominal Swelling

Dyspnea


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