A Patient Centered Approach to Hypophosphatemia: Diagnosis, Evaluation, and Treatment- Enduring

This course was a live CME-certified Ancillary Symposium presented at ENDO 2019 (March 23, 2019), held in New Orleans, LA. This educational activity is supported by an independent medical educational grant from Ultragenyx Pharmaceuticals. These ancillary symposia are developed through the Endocrine Society’s Special Programs Committee (SPC).

Watch the following 5 short modules:

  1. Introduction to Hypophosphatemia
  2. Diagnosis and Evaluation of Hypoposphatemia
  3. Treatment of non-FGF-23 Mediated Hypophosphatemic Disorders
  4. Treatment of FGF-23 Mediated Hypophosphatemic Disorders
  5. Panel Discussion








Target Audience

This activity is intended for endocrinologists and endocrine fellows, primary care physicians, physician’s assistants, nurse practitioners, and other healthcare professionals.

Learning Objectives

Upon completing this activity, learners will be able to:

  • Incorporate best practices for evaluating and diagnosing patients with hypophosphatemia in their practice.
  • Discuss pathophysiology and treatment strategies for patients with FGF-23 mediated phosphate disorders.
  • Discuss pathophysiology and treatment strategies for patients with non-FGF-23 mediated phosphate disorders.

Additional Information

Target Audience: 
Clinical researcher
Scientific researcher
Nurse/Nurse practitioner
Physician assistant
Allied health professional
Competency Area: 
Medical Knowledge
Topic Area: 
Bone and Calciotropic Hormones
General Endocrinology
Level of Outcomes: 
Level 1 (Participation)
Level 2 (Satisfaction)
Level 3A (Learning: Declarative Knowledge (Knows))
Level 4 (Learning: Competence (Shows How))
Level 5 (Performance (Does))
Activity summary
Available credit: 
  • 2.00 ABIM MOC
  • 2.00 AMA PRA Category 1 Credits
  • 2.00 CME Certificate of Participation
Course opens: 
Course expires: 

Program Director

Anda R. Gonciulea, MD
Yale New Haven Northeast Medical Group
Stratford, CT


Suzanne Jan De Beur, MD
Associate Professor/ Director
Johns Hopkins University 
Baltimore, MD
Peter J. Tebben, MD
Mayo Clinic
Rochester, MN
Michael P. Whyte, MD
Washington University 
Medical Scientific Director
Shriners Hospitals for Children-St. Louis
St. Louis, MO


The faculty, committee members, and staff who are in position to control the content of this activity are required to disclose to the Endocrine Society and to learners any relevant financial relationship(s) of the individual or spouse/partner that have occurred within the last 12 months with any commercial interest(s) whose products or services are related to the CME content. Financial relationships are defined by remuneration in any amount from the commercial interest(s) in the form of grants; research support; consulting fees; salary; ownership interest (e.g., stocks, stock options, or ownership interest excluding diversified mutual funds); honoraria or other payments for participation in speakers' bureaus, advisory boards, or boards of directors; or other financial benefits. The intent of this disclosure is not to prevent CME planners with relevant financial relationships from planning or delivery of content, but rather to provide learners with information that allows them to make their own judgments of whether these financial relationships may have influenced the educational activity with regard to exposition or conclusion.

The Endocrine Society has reviewed all disclosures and resolved or managed all identified conflicts of interest, as applicable.

The following faculty reported no relevant financial relationships during the content development process for this activity: 
Anda R. Gonciulea, MD

The faculty reported the following relevant financial relationship(s) during the content development process for this activity:
Daniel .H. Bessesen: Data Safety Board Member: Enteromedics
Suzanne M. Jan De Beur, MD: Advisory Board Member: Ultragenyx; Grant Recipient: Ultragenyx, Mereo Biopharma
Peter J. Tebben, MD: Research Investigator: Ultragenyx
Michael P. Whyte, MD: Grant Recipient, Ultragenyx; Research Investigator, Ultragenyx

The following SPC member who planned and reviewed content for this activity reported no relevant financial relationships: 
Deborah Sellmeyer, MD

The following SPC members reported relevant financial relationships:
Amy Rothberg, MD: Spouse, consultant of Merck
Andrew Ahmann, MD:Research Support, Dexcom, Medtronic; Consultant, Dexcom, Eli Lilly & Company, Horizon CME, MannKind, Novo Nordisk, Sanofi; Speaker, Horizon CME; Principle Investigator, National Institute of Health, T1D Exchange, Trial Net
Giuseppe Barbesino, MD: Advisory Boards, Horizon Pharmaceuticals, Ipsen Pharmaceuticals; Spouse, employee of Genzyme
Joan Han, MD:Research Support, Rhythm Pharmaceuticals; Principle Investigator, Insys Therapeutics, Rhythm Pharmaceuticals
Steven T. Harris, MD:Ad hoc consultant on Advisory Boards, Eli Lilly & Company, Radius Health; Speaker, Amgen, Eli Lilly & Company, Radius Health
Jonathan Purnell, MD: Advisor, Novo Nordisk
Neda Rasouli, MD:Research Support, Novo Nordisk, Boehringer Ingelheim, Rhythm Pharmaceuticals, Elira Therapeutics; Consultant, Intarcia
Amy Rothberg, MD:Spouse, consultant of Merck
Susmeeta Sharma, MD: Speaker, Corcept

The Endocrine Society has reviewed these relationships to determine which are relevant to the content of this activity and resolved any identified conflicts of interest for these individuals.

The following SPC members reported no relevant financial relationships:
Beret Ann Casey, MD; Lorena Alarcon-Casas Wright, MD, Neena Natt, MD; 

Endocrine Society staff associated with the development of content for this activity reported no relevant financial relationships.


Click "Start" to complete the meeting evaluation, claim CME, and print a certificate of attendance or certificate of participation.

The Endocrine Society is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The Endocrine Society has achieved Accreditation with Commendation.

The Endocrine Society designates this live activity for a maximum of 2.0 AMA PRA Category 1 Credit™ and 2.0 ABIM MOC Points. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


For questions about content or obtaining CME credit, please contact the Endocrine Society at education.endocrine.org/contact



Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 2.0 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. 


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Available Credit

  • 2.00 ABIM MOC
  • 2.00 AMA PRA Category 1 Credits
  • 2.00 CME Certificate of Participation