ESAP: Special Edition


The Endocrine Self-Assessment Program (ESAP™) is a self-study curriculum for clinicians wanting a self-assessment and a broad review of endocrinology. This special edition of ESAP consists of 27 brand-new case vignettes with extensive discussion of the correct answer along with a historical perspective and the applications to clinical practice today. The topics included within this publication were selected to highlight the expertise and contributions of the past presidents recognized herein. This body of work is not an attempt to adequately cover the field of clinical endocrinology

ESAP is composed of two key components: the initial online interactive module and the printed book. Upon purchase, learners will initially receive access to the online module. To use ESAP as a true self-assessment tool, learners are strongly encouraged to complete the online interactive self-assessment module first before continuing self-study with the printed book; the online module may be accessed at


Target Audience

ESAP is a self-study curriculum aimed at physicians seeking initial certification or recertification in endocrinology, program directors interested in a testing and training instrument, and clinicians simply wanting a self-assessment and a broad review of endocrinology.

Learning Objectives

Upon completion of this educational activity, participants will be able to:

  • Recognize clinical manifestations of endocrine and metabolic disorders and select among current options for diagnosis, management, and therapy.
  • Identify risk factors for endocrine and metabolic disorders and develop strategies for prevention.
  • Evaluate endocrine and metabolic manifestations of systemic disorders.
  • Apply historical foundations to today's clinical practice.

Additional Information

Target Audience: 
Clinical researcher
Scientific researcher
Nurse/Nurse practitioner
Physician assistant
Allied health professional
Competency Area: 
Medical Knowledge
Topic Area: 
Adrenal/HPA Axis
Bone and Calciotropic Hormones
Diabetes and Glucose Metabolism
Lipid Disorders and Fatty Liver Diseases
Quality Improvement and Healthcare Delivery
General Endocrinology
Growth Disorders
Health Disparities
Hormones and Cancer
Men’s Health
Neuroendocrinology and Pituitary
Pediatric Endocrinology
Thyroid/HPT Axis
Women’s Health
Level of Outcomes: 
Level 1 (Participation)
Level 2 (Satisfaction)
Level 3A (Learning: Declarative Knowledge (Knows))
Level 3B (Learning: Procedural Knowledge (Knows How))
Activity summary
Available credit: 
  • 10.00 ABIM MOC
  • 10.00 AMA PRA Category 1 Credits
  • 10.00 CME Certificate of Participation
Course opens: 
Course expires: 
In-Training/Early Career Member


Alan C. Dalkin, MD, Faculty Chair
ESAP Chair (2011-2015)
ESAP Faculty (2000-2010)
University of Virginia

Andrew J. Bauer, MD
Pediatric ESAP Faculty (2014-Present)
Children’s Hospital of Philadelphia

Jan M. Bruder, MD
ESAP Faculty (2006-2011)
University of Texas Health Science Center-San Antonio

James W. Findling, MD
ESAP Faculty (2010-2015)
Medical College of Wisconsin

Rachel I. Gafni, MD
Pediatric ESAP Chair (2015-Present)
Pediatric ESAP Faculty (2014-2015)
Bethesda, Maryland

Oksana Lekarev, DO
Pediatric ESAP Faculty (2014-Present)
Weill Cornell Medical College

Elaine M. Pelley, MD
ESAP-ITE Steering Group (2015-Present)
University of Wisconsin

Liuska M. Pesce, MD
Pediatric ESAP Faculty (2015-Present)
University of Iowa

Lawrence A. Silverman, MD
Pediatric ESAP Faculty (2013-Present)
Goryeb Children’s Hospital

Lisa R. Tannock, MD
ESAP Chair (2016-Present)
ESAP Faculty (2011-2015)
University of Kentucky and Department of Veterans Affairs

Corrine K. Welt, MD
ESAP Faculty (2012-Present)
University of Utah School of Medicine

William F. Young Jr, MSc, MD
ESAP Chair (2007-2011)
ESAP Faculty (2002-2006)
Mayo Clinic College of Medicine



Maria L. Collazo-Clavell, MD
ESAP Faculty (2011-2016)
Mayo Clinic College of Medicine

Marie Freel, MB, ChB, PhD
ESAP Faculty (2013-Present)
Queen Elizabeth University Hospital

Jennifer B. Green, MD
ESAP Faculty (2012-2016)
Duke University Medical Center

Mimi I-Nan Hu, MD
ESAP Faculty (2015-Present)
University of Texas MD Anderson Cancer Center

Michael S. Irwig, MD
ESAP Faculty (2015-Present)
George Washington University

Jacqueline Jonklaas, MD, PhD
ESAP Faculty (2013-Present)
Georgetown University

Steven B. Magill, MD
ESAP Faculty (2015-Present)
Medical College of Wisconsin

Savitha Subramanian, MD
ESAP Faculty (2015-Present)
University of Washington

Nicholas A. Tritos, MD, DSc
ESAP Faculty (2014-2016)
Massachusetts General Hospital & Harvard Medical School

Adrian V. Vella, MD
ESAP Faculty (2009-2015)
Mayo Clinic College of Medicine

Abbie L. Young, MS, CGC, ELS(D)
Medical Editor

As a provider of CME accredited by the Accreditation Council for Continuing Medical Education, the Endocrine Society has a policy of ensuring that the content and quality of this educational activity are balanced, independent, objective, and scientifically rigorous. The scientific content of this activity was developed by expert faculty.

The faculty and staff who are in position to control the content of this activity are required to disclose to the Endocrine Society and to learners any relevant financial relationship(s) of the individual or spouse/ partner that have occurred within the last 12 months with any commercial interest(s) whose products or services are related to the CME content. Financial relationships are defined by remuneration in any amount from the commercial interest(s) in the form of grants; research support; consulting fees; salary; ownership interest (eg, stocks, stock options, or ownership interest excluding diversified mutual funds); honoraria or other payments for participation in speakers’ bureaus, advisory boards, or boards of directors; or other financial benefits. The intent of this disclosure is not to prevent CME planners with relevant financial relationships from planning or delivering content, but rather to provide learners with information that allows them to make their own judgments of whether these financial relationships may have influenced the educational activity with regard to exposition or conclusion. The Endocrine Society has reviewed all disclosures and resolved or managed all identified conflicts of interest, as applicable.

The following faculty reported relevant financial relationship(s): James W. Findling, MD, is an investigator/consultant for Corcept Therapeutics, Millendo, Diurnal and Novartis. Duke University receives funds from Merck, AstraZeneca, and GlaxoSmithKline for research performed by Jennifer Green, MD. These funds support a portion of her salary. Dr. Green has also received honoraria from Merck, Daiichi and Boehringer Ingelheim for serving as a consultant, and honoraria from Bioscientifica for editorial activities. Mimi Hu, MD, is a consultant for Eisai and Genzyme. Lawrence Silverman, MD, is a consultant/Advisor for Opko Biologics, Endo Pharmaceuticals, Novo Nordisk and Abbvie and is a contracted researcher for Novo Nordisk and Versartis. He is also a speaker for Abbvie. Savitha Subramanian, MD, has received grant support from Ionis Pharmaceuticals. Nicholas A. Tritos, MD, receives research support from Ipsen, Us, Pfizer, Inc, Novo Nordisk and Novartis; his spouse is an employee of Pfizer, Inc. Adrian V. Vella, MD, is funded by the National Institutes of Health (DK78646). He is an investigator in multicenter studies sponsored by Novartis and GI dynamics, respectively. He has consulted for XOMA, Sanofi-Aventis, Novartis and Bristol-Myers Squibb in the past 5 years. Corrine Welt, MD, is a writer for UpToDate and a consultant for Takeda. William Young, Jr, MD, is a consultant for Nihon Medi-Physics.          

The following faculty members reported no relevant financial relationships: Andrew Bauer, MD; Janet Bruder, MD; Maria L. Collazo-Clavell, MD; Alan C. Dalkin, MD; Marie Freel, MB,ChB, PhD; Rachel Gafni, MD; Michael Irwig, MD; Jacqueline Jonklaas, MD, PhD; Oksana Lekarev, DO; Steven Magill, MD; Elaine Pelley, MD; Liuska Pesce, MD; and Lisa R. Tannock, MD.

The medical editor for this program, Abbie L. Young, MS, CGC, ELS(D), reported no relevant financial relationships.

The Endocrine Society staff associated with the development of content for this activity reported no relevant financial relationships.

The information presented in this activity represents the opinion of the faculty and is not necessarily the official position of the Endocrine Society.

The educational content in this self-assessment test relates to basic principles of diagnosis and therapy and does not substitute for individual patient assessment based on the health care provider’s examination of the patient and consideration of laboratory data and other factors unique to the patient. Standards in medicine change as new data become available.

When prescribing medications, the physician is advised to check the product information sheet accompanying each drug to verify conditions of use and to identify any changes in drug dosage schedule or contraindications.

The Endocrine Society has determined that disclosure of unlabeled/off-label or investigational use of commercial product(s) is informative for audiences and therefore requires this information to be disclosed to the learners at the beginning of the presentation. Uses of specific therapeutic agents, devices, and other products discussed in this educational activity may not be the same as those indicated in product labeling approved by the Food and Drug Administration (FDA). The Endocrine Society requires that any discussions of such “off-label” use be based on scientific research that conforms to generally accepted standards of experimental design, data collection, and data analysis. Before recommending or prescribing any therapeutic agent or device, learners should review the complete prescribing information, including indications, contraindications, warnings, precautions, and adverse events.

The Endocrine Society will record learner’s personal information as provided on CME evaluations to allow for issuance and tracking of CME certificates. The Endocrine Society may also track aggregate responses to questions in activities and evaluations and use these data to inform the ongoing evaluation and improvement of its CME program. No individual performance data or any other personal information collected from evaluations will be shared with third parties.

This activity has not received commercial support.

Accreditation Statement

The imageEndocrine Society is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The Endocrine Society has achieved Accreditation with Commendation.

The Endocrine Society designates this enduring material for a maximum of 10.0 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Maintenance of Certification

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 10 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

Available Credit

  • 10.00 ABIM MOC
  • 10.00 AMA PRA Category 1 Credits
  • 10.00 CME Certificate of Participation

Course closed

This course closed on Friday, January 24, 2020 - 11:59pm.

Required Hardware/software

To complete this activity, participants must have access to a computer or mobile device with an Internet connection and use a major Web browser, such as Internet Explorer 10+, Firefox 32+, Safari, or Google Chrome 37+. In addition, cookies and Javascript must be enabled in the browser’s options.