Turner syndrome is one of the most common chromosomal anomalies in females, caused by loss of part of X chromosome or all of it. Its incidence varies from 1 in 2000 to 1 in 2500 live female births. It is an important cause of short stature and primary and or premature ovarian insufficiency in females. It also affects other organ systems and females with this condition are at high risk of developing various multisystem manifestations including hypertension, aortic root dilatation and dissection, renal anomalies, osteoporosis, fatty liver, high risk of malignancies, metabolic syndrome, type 2 diabetes, and hearing abnormalities. In most of the females, short stature, abnormalities of menstruation, and puberty are the presenting symptoms. Endocrinologists are usually involved in the care of these patient early on. However, in view of multisystem involvement, a coordinated holistic approach is required for the better outcomes in these patients. Endocrinologists are well placed to take the lead in holistic care of these patients and coordinate multidisciplinary care.

At The Christie Hospital, Manchester, we hold a dedicated Turner syndrome service. Holistic approach in long-term management of these patients will be discussed.

The intended audience for this activity includes a wide range of health care professionals; many may deem this presentation beneficial.

1. To learn about the diagnosis and different presentations of Turner syndrome
2. To learn about different systemic manifestations of Turner syndrome
3. To learn about long-term, follow up, and management of different systemic manifestations of Turner syndrome
4. To learn about coordination of holistic care of a patient with Turner syndrome with various other specialties, to improve long term outcomes

The Endocrine Society is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Endocrine Society has achieved Accreditation with Commendation.

AMA PRA Category 1 Credit
The Endocrine Society designates each activity in this course for a maximum of 1.00 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. While offering CME credits noted above, this program is not intended to provide extensive training or certification in the field.

Please note that while other accrediting bodies accept AMA PRA Category 1 credit, we can only award and report this credit for MDs/DOs. For those outside of this accreditation, please complete the participation evaluation and use that certificate as proof of attendance to submit to your accrediting body.

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Successful completion of each CME activity in this course, which includes participation in the evaluation component, enables the participant to earn up to 1.00 points in the American Board of Internal Medicine (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

For questions about content or obtaining CME credit, please contact the Endocrine Society at info@endocrine.org

FACULTY AND DISCLOSURES

Shaishav Dhage, MBBS, DNB,MRCP, MD 
The Christie NHS Foundation Trust 

STATEMENT OF INDEPENDENCE
As a provider of CME accredited by the ACCME, the Endocrine Society has a policy of ensuring that the content and quality of this educational activity are balanced, independent, objective, and scientifically rigorous. The scientific content of this activity was developed under the supervision of the Endocrine Society's EBR faculty. There are no commercial supporters of this activity, and no commercial entities have had influence over the planning of this CME activity.

DISCLOSURE POLICY
The faculty, committee members, and staff who are in position to control the content of this activity are required to disclose to the Endocrine Society and to learners any relevant financial relationship(s) of the individual or spouse/partner that have occurred within the last 12 months with any commercial interest(s) whose products or services are related to the CME content. Financial relationships are defined by remuneration in any amount from the commercial interest(s) in the form of grants; research support; consulting fees; salary; ownership interest (eg, stocks, stock options, or ownership interest excluding diversified mutual funds); honoraria or other payments for participation in speakers' bureaus, advisory boards, or boards of directors; or other financial benefits. The intent of this disclosure is not to prevent CME planners with relevant financial relationships from planning or delivery of content, but rather to provide learners with information that allows them to make their own judgments of whether these financial relationships may have influenced the educational activity regarding exposition or conclusion. 

The faculty reported no relevant financial relationships.
The Endocrine Society staff report no relevant financial relationships.